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The long reach of noncoding RNAs. PDF Print E-mail
Journal: Nat Genet
Authors: Sotillo E, Thomas-Tikhonenko A
Published: 2011;43(7):616-7
Pubmed ID: 21709680

Transcription of genomic loci containing protein-coding genes often yields not only cognate mRNAs but also assorted noncoding RNAs (ncRNAs), which typically map in the vicinity of transcription start sites. A new study shows that far from being random byproducts of gene expression, many long ncRNAs (lncRNAs) are synthesized in a coordinate fashion and control important cellular processes, such as survival in the face of DNA damage.